Domestic benchmark index NSE Nifty ended 92.21 points down at 22460.3, while the BSE Sensex closed 217.41 points down at 74115.17.
On the other hand, Nitiraj Engineers, AXISCADES Engg Tech, Reliance Naval & Engg, California Soft(PP)and Steel Cast stocks hit their fresh 52-week highs today.
In the Nifty 50 index, Power Grid, HUL, Infosys, SBI Life and Nestle India were among the top gainers on the NSE in the today's trade.
Meanwhile, ONGC, Trent, IndusInd Bank, Bajaj Auto and Eicher Motors were among the top losers of the day.