MULTI DRUG RESISTANT
Wockhardt chairman seeks GST exemption for antibiotics discovered in India
Wockhardt founder sought GST exemption for antibiotics discovered in India. He said this will make the drugs more affordable. The statement was made at an event to celebrate the scientific completion of the first indigenously developed antibiotic Nafithromycin. Nafithromycin is the first macrolide antibiotic in 30 years for community-acquired bacterial pneumonia.
Through collective spirit, we'll keep working towards TB-free India: PM Modi
Prime Minister Narendra Modi acknowledged India's dedicated efforts leading to a significant decline in TB incidence. Health Minister J P Nadda highlighted the WHO's recognition of India's progress and the government's initiatives like the Ni-Kshay Poshan Yojana and BPALM regimen. The united spirit and healthcare workers' commitment continue to drive the fight against tuberculosis.
How an 80-year-old antibiotic can become a wonder drug to defeat world's most dangerous infections
Researchers are studying streptothricin, an old antibiotic, for its potential to fight drug-resistant superbugs. The antibiotic, now named nourseothricin, was initially sidelined due to toxicity concerns. With the rise of multi-drug-resistant pathogens, there is renewed interest in its use as a possible solution to antibiotic resistance.
Emcure Pharmaceuticals partners with Gilead Sciences to produce HIV prevention drug Lenacapavir
Emcure Pharmaceuticals has partnered with Gilead Sciences Ireland UC to manufacture and distribute generic lenacapavir for HIV prevention and treatment. This royalty-free agreement focuses on increasing access to the drug in 120 countries, especially resource-limited nations. Emcure aims to provide high-quality, low-cost HIV medication to improve health outcomes globally.
Dr Reddy's enters voluntary licensing deal with Gilead for long-acting HIV drug
Dr. Reddy¡¯s has partnered with Gilead Sciences to manufacture and market the HIV drug Lenacapavir in India and 120 other countries. The agreement includes developing Lenacapavir for both treatment and potential prevention of HIV. This collaboration aims to make this advanced treatment accessible in regions with high HIV burdens.
Can Kerala's antibiotic abuse project inspire India's antimicrobial resistance fight?
In 2019, nearly 300,000 deaths in India were due to AMR. Over 1 million deaths were linked to drug resistance, making infections more challenging to treat. Kerala initiated an AMR action plan in 2018. However, analysts say that Kerala¡¯s approach might not be directly applicable to other states, where access to antibiotics is itself an issue.
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No shortage of anti-TB drugs in India, asserts Health Ministry
The treatment regimen of multi drug resistant TB consists of usually four months of seven drugs (bedaquiline, levofloxacin, clofazimine, isoniazid, ethambutol, pyrazinamide and ethionamide) followed by five months of 4 drugs (levofloxacin, clofazimine, pyrazinamide and ethambutol). In about 30 pc of persons with drug resistant TB, cycloserine and linezolid is required.
ICMR worried over rising resistance to last-resort antibiotics in India
ICMR has found the abuse of antimicrobials (antibiotics, antivirals or antifungals) to be the reason for this, which is says has led to widespread resistance among people.
Candida auris: All you need to know about the deadly fungus spreading across the U.S
Some strains of Candida auris are categorized as superbugs due to their resistant to all three classes of antifungal medication used to treat such infections.
CDSCO suspends manufacturing of eye drops linked to 55 adverse events in United States
According to the people aware of the matter, the US-based Food and Drug Administration has warned the consumers "not to purchase or use EzriCare Artificial Tears due to potential contamination", and the Union Health Ministry's CDSCO and Tamil Nadu's State Drug Controller have initiated a probe into the matter.
Indian drug firm recalls eye drop linked to vision loss in US
In a statement posted on its website, Global Pharma Healthcare said it is notifying the distributors of this product Aru Pharma Inc and Delsam Pharma, and is requesting that wholesalers, retailers and customers who have the recalled product should stop using it. Consumers should contact their physician or healthcare provider if they have experienced any problems that may be related to using these over-the-counter drug products, it said.
Sustained rise in antimicrobial resistance in India: ICMR study
This is the fifth detailed report on antimicrobial resistance (AMR) trends and patterns from the country published by the ICMR. This year's report also carries hospital-acquired surveillance data. According to the report, resistance to Imipenem, which is used to treat infections caused by bacteria E coli, has increased from 14 per cent in 2016 to 36 per cent in 2021.
Typhoid bacteria more resistant to antibiotics now: Lancet study
According to the study, quinolone-resistant strains accounted for more than 85% of S Typhi (the bacteria that causes Typhoid fever) in Bangladesh by the early 2000s, increasing to more than 95% in India, Pakistan and Nepal by 2010.
Pharma companies are now busy adding capacities and seeing a surge in demand for non-Covid drugs
Indian drug manufacturers launch 300-350 new brands (mostly repurposed or combinations of two earlier drugs) every year. This had slowed down in the initial months of Covid-19 as most companies were trying to assess the situation. But with Covid cases falling, new launches are almost back to preCovid levels, say drug wholesalers
Oxford University's new mega centre to combat global antibiotic resistance
The university experts warn that it is arguably the greatest economic and healthcare challenge facing the world post-Covid and therefore the new Ineos Oxford Institute (IOI) is being set up to create collaborative and cross-disciplinary links across the sciences.
C-CAMP kicks off programme for antimicrobial resistance innovations
The programme, which was announced at the Grand Finale of the C-CAMP AMR Quest held in July 2020, has been kicked off with six innovators in therapeutics and diagnostics.
IIT Roorkee researchers find antibiotic against multi-drug resistant bacteria
In a new study published in the journal, ¡®Journal of Antimicrobial Chemotherapy¡¯, IIT Roorkee researchers screened a library of 11,000 compounds against the Gram negative bacteria, Escherichia coli and discovered 30 novel potent antibacterials.
WHO announces important changes to multi drug resistant TB treatment
In its last-issued guidance in October 2016, the WHO had restricted usage to the breakthrough drug owing to concerns around its effect on the heart (cardio-toxicity).
World TB Day: Over 25% TB patients in India are resistant to at least one anti-TB drug
"High rates of treatment failure and deaths are associated with fluoroquinolone resistance in the Indian cohort of MDR-TB patients," stated the study.
This type of onion can help fight drug-resistant tuberculosis
When a patient has a bacterial TB infection, they may be prescribed an antibiotic.
'Drug-resistant organisms causing spike in infectious diseases'
New Delhi, Nov 17 (IANS) Multi Drug Resistant organisms that cause deadly infections are spreading resulting in community-acquired infections, reveals a new study by city's Sir Ganga Ram Hospital (SRGH).
Drug resistance making typhoid tough to treat
Doctors say that while earlier oral drugs could cure most patients, they now need to give injectable antibiotics to 20-30% of the patients to treat typhoid symptoms.
India urged to intensify research for multi-drug resistant TB
New Delhi, March 23 (IANS) As India continues to have 24 per cent of the world's total Tuberculosis (TB) burden, the Indian Society for Clinical Research (ISCR) on Thursday called for a comprehensive research in multi-drug resistant Tuberculosis, citing that resistance to antimicrobials is growing at a faster rate than discovery of newer and more potent drugs.
PM Modi takes pledge to support AMR; economic cost could hit $100 tn by 2050
The global costs, if we do not take action now, could be 10 million people dying every year by 2050, and a cumulative economic cost of around $100 trillion.
Government to curb prescription and sale of antibiotics to combat drug resistance
This means doctors and chemists will have to follow certain mandatory protocols and guidelines while prescribing antibiotics.
WHO adopts new global strategy to fight drug-resistant diseases
India accounts for the highest number of tuberculosis cases, it is also the hub of multi-drug resistant (MDR) tuberculosis.
CSIR's OSDD project comes to an end
The Open Source Drug Discovery project of the Council of Scientific and Industrial Research was meant to discover drugs for neglected diseases.
Uncertainty in regulatory regime forcing Indian firms like Biocon shift drug trials abroad
Blame administrative lethargy, not judicial overreach, for regulatory vacuum, making India forgo a valuable economic activity, which raises cost of new Indian drugs.
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